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Stupefied
Status penalty equal to the condition's value applies to all Intelligence-, Wisdom-, and Charisma-based rolls and DCs, including spell attack rolls and spell DCs. Casting a spell r...
Stupefied always includes a value. You take a status penalty equal to that value to all Intelligence-, Wisdom-, and Charisma-based rolls and DCs, including spell attack rolls and spell DCs. If you try to Cast a Spell, you must succeed at a flat check (DC = 5 + Stupefied value) or the spell is lost.
Stupefied is the primary condition used to shut down spellcasters and mentally-dependent abilities. Even Stupefied 1 can cause meaningful spell loss on a bad roll.